Aggregation-Induced Emission Luminogens Realizing High-Contrast Bioimaging

A revolutionary transformation in biomedical imaging is unfolding with the advent of aggregation-induced emission luminogens (AIEgens). These cutting-edge molecules not only overcome the limitations of traditional fluorescent probes but also improve the boundaries of high-contrast imaging. Unlike conventional fluorophores suffering from aggregation-caused quenching, AIEgens exhibit enhanced luminescence when aggregated, enabling superior imaging performance. This review delves into the molecular mechanisms of aggregation-induced emission (AIE), demonstrating how strategic molecular design unlocks exceptional luminescence and superior imaging contrast, which is crucial for distinguishing healthy and diseased…

• NN
  National Natural Science Foundation of China

  Awards: 52333007, 52273197
• CP
  China Postdoctoral Science Foundation

  Award: 2023M733423
• ST
  Science, Technology and Innovation Commission of Shenzhen Municipality

  Awards: JCYJ20220818103007014, GJHZ20210705141810031, JCYJ2021324134613038, KQTD20210811090142053
• GM
  Guangzhou Municipal Science and Technology Project

  Award: 2023A04J0069
• NK
  National Key Research and Development Program of China

  Award: 2023YFB3810001