Radiopharmaceuticals and their applications in medicine

Abstract Radiopharmaceuticals involve the local delivery of radionuclides to targeted lesions for the diagnosis and treatment of multiple diseases. Radiopharmaceutical therapy, which directly causes systematic and irreparable damage to targeted cells, has attracted increasing attention in the treatment of refractory diseases that are not sensitive to current therapies. As the Food and Drug Administration (FDA) approvals of [ 177 Lu]Lu-DOTA-TATE, [ 177 Lu]Lu-PSMA-617 and their complementary diagnostic agents, namely, [ 68 Ga]Ga-DOTA-TATE and [ 68 Ga]Ga-PSMA-11, targeted radiopharmaceutical-based theranostics (radiotheranostics) are being increasingly implemented in clinical practice in oncology, which lead to a…

• NN
  National Natural Science Foundation of China

  Award: 82372002
• CN
  China National Nuclear Corporation
• FR
  Fundamental Research Funds for the Central Universities

  Awards: 3332023044, 3332023151