articleScientific ReportsJan 2, 2025GOLD OA

pACP-HybDeep: predicting anticancer peptides using binary tree growth based transformer and structural feature encoding with deep-hybrid learning

Abdul Wali Khan University Mardan · King Abdulaziz University · +3 more institutions

PubMed
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Abstract

Worldwide, Cancer remains a significant health concern due to its high mortality rates. Despite numerous traditional therapies and wet-laboratory methods for treating cancer-affected cells, these approaches often face limitations, including high costs and substantial side effects. Recently the high selectivity of peptides has garnered significant attention from scientists due to their reliable targeted actions and minimal adverse effects. Furthermore, keeping the significant outcomes of the existing computational models, we propose a highly reliable and effective model namely, pACP-HybDeep for the accurate prediction of anticancer peptides. In this model, training peptides are numerically encoded using an…

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68
total citations
FWCI
45.57
Percentile
100%
References
84
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Authors

7

Topics & keywords

Keywords
  • Computer science
  • Artificial intelligence
  • Machine learning
  • Encoder
  • Deep learning
  • Support vector machine
  • Feature (linguistics)
UN Sustainable Development Goals
  • Good health and well-being
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