articleACS NanoJan 3, 2025Closed access

Magnetic Nanoactuator-Protein Fiber Coated Hydrogel Dressing for Well-Balanced Skin Wound Healing and Tissue Regeneration

CHChenlong HeMYMing YinHZHan ZhouJQJingwen QinSWSheng‐Ming Wu

Shanghai East Hospital

PubMed
Indexed incrossrefpubmed

Abstract

Despite significant progress in skin wound healing, it is still a challenge to construct multifunctional bioactive dressings based on a highly aligned protein fiber coated hydrogel matrix for antifibrosis skin wound regeneration that is indistinguishable to native skin. In this study, a “dual-wheel-driven” strategy is adopted to modify the surface of methacrylated gelatin (GelMA) hydrogel with highly aligned magnetic nanocomposites-protein fiber assemblies (MPF) consisting of photothermal responsive antibacteria superparamagnetic nanocomposites-fibrinogen (Fg) complexes as the building blocks. Whole-phase healing properties of the modified hydrogel dressing, GelMA-MPF (GMPF), stem from the integration of Fg…

Citation impact

44
total citations
FWCI
33.96
Percentile
100%
References
59
Citations per year

Authors

11

Topics & keywords

Topics
Keywords
  • Regeneration (biology)
  • Wound healing
  • Gelatin
  • Materials science
  • Biomedical engineering
  • Extracellular matrix
  • Skin repair
  • Biophysics
UN Sustainable Development Goals
  • Zero hunger
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