articleNature MedicineJan 7, 2025HYBRID OA

Nationwide real-world implementation of AI for cancer detection in population-based mammography screening

NENora EisemannSBStefan BunkTMTrasias MukamaHBHannah BaltusSESusanne Elsner

University of Lübeck · Varian Medical Systems (Switzerland) · +1 more institution

PubMed
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Abstract

Artificial intelligence (AI) in mammography screening has shown promise in retrospective evaluations, but few prospective studies exist. PRAIM is an observational, multicenter, real-world, noninferiority, implementation study comparing the performance of AI-supported double reading to standard double reading (without AI) among women (50-69 years old) undergoing organized mammography screening at 12 sites in Germany. Radiologists in this study voluntarily chose whether to use the AI system. From July 2021 to February 2023, a total of 463,094 women were screened (260,739 with AI support) by 119 radiologists. Radiologists in the AI-supported screening group achieved a breast cancer detection rate of 6.7 per…

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Topics & keywords

Topics
Keywords
  • Mammography
  • Medicine
  • Confidence interval
  • Breast cancer
  • Observational study
  • Recall
  • Breast cancer screening
  • Gynecology
UN Sustainable Development Goals
  • Quality Education
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