A rare PRIMER cell state in plant immunity
University of East Anglia · Salk Institute for Biological Studies · +6 more institutions
Abstract
Abstract Plants lack specialized and mobile immune cells. Consequently, any cell type that encounters pathogens must mount immune responses and communicate with surrounding cells for successful defence. However, the diversity, spatial organization and function of cellular immune states in pathogen-infected plants are poorly understood 1 . Here we infect Arabidopsis thaliana leaves with bacterial pathogens that trigger or supress immune responses and integrate time-resolved single-cell transcriptomic, epigenomic and spatial transcriptomic data to identify cell states. We describe cell-state-specific gene-regulatory logic that involves transcription factors, putative cis -regulatory elements and target genes…
Citation impact
- FWCI
- 108.42
- Percentile
- 100%
- References
- 73
Authors
9- TNTatsuya NoboriCorresponding
University of East Anglia, Salk Institute for Biological Studies, Howard Hughes Medical Institute, Sainsbury Laboratory
- AMAlexander Monell
Salk Institute for Biological Studies, University of California San Diego
- TLTravis Lee
Salk Institute for Biological Studies, Howard Hughes Medical Institute
- YSYuka Sakata
Kyoto University
- SSShoma Shirahama
Kyoto University
Topics & keywords
- Immune system
- Biology
- Population
- Immunity
- Cell biology
- Cell
- Arabidopsis
- Transcriptome