reviewnpj Biofilms and MicrobiomesJan 10, 2025GOLD OA

The oral-gut microbiota axis: a link in cardiometabolic diseases

Chinese Academy of Medical Sciences & Peking Union Medical College · Xiyuan Hospital

PubMed
Indexed incrossrefdoajpubmed

Abstract

The oral-gut microbiota axis plays a crucial role in cardiometabolic health. This review explores the interactions between these microbiomes through enteric, hematogenous, and immune pathways, resulting in disruptions in microbial balance and metabolic processes. These disruptions contribute to systemic inflammation, metabolic disorders, and endothelial dysfunction, which are closely associated with cardiometabolic diseases. Understanding these interactions provides insights for innovative therapeutic strategies to prevent and manage cardiometabolic diseases.

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