Emerging role of exosomes in cancer therapy: progress and challenges
Central South University · Haikou City People's Hospital
Abstract
This review highlights recent progress in exosome-based drug delivery for cancer therapy, covering exosome biogenesis, cargo selection mechanisms, and their application across multiple cancer types. As small extracellular vesicles, exosomes exhibit high biocompatibility and low immunogenicity, making them ideal drug delivery vehicles capable of efficiently targeting cancer cells, minimizing off-target damage and side effects. This review aims to explore the potential of exosomes in cancer therapy, with a focus on applications in chemotherapy, gene therapy, and immunomodulation. Additionally, challenges related to exosome production and standardization are analyzed, highlighting the importance of addressing…
Citation impact
- FWCI
- 118.34
- Percentile
- 100%
- References
- 297
Authors
3Topics & keywords
- Microvesicles
- Biology
- Cancer therapy
- Cancer
- Cancer research
- Computational biology
- microRNA
- Genetics