Selective utilization of medicinal polysaccharides by human gut Bacteroides and Parabacteroides species
Macau University of Science and Technology · Chinese Academy of Sciences · +8 more institutions
Abstract
Human gut Bacteroides and Parabacteroides species play crucial roles in human health and are known for their capacity to utilize diverse polysaccharides. Understanding how these bacteria utilize medicinal polysaccharides is foundational for developing polysaccharides-based prebiotics and drugs. Here, we systematically mapped the utilization profiles of 20 different medicinal polysaccharides by 28 human gut Bacteroides and Parabacteroides species. The growth profiles exhibited substantial variation across different bacterial species and medicinal polysaccharides. Ginseng polysaccharides promoted the growth of multiple Bacteroides and Parabacteroides species; in contrast, Dendrobium polysaccharides selectively…
Citation impact
- FWCI
- 44.93
- Percentile
- 100%
- References
- 98
Authors
19- ZQZepeng Qu
Macau University of Science and Technology, Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology
- HLHongbin Liu
Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology
- YJYang Ji
Guangdong Pharmaceutical University
- LZLinggang Zheng
Macau University of Science and Technology, Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology
- JHJumin Huang
University of Macau
Topics & keywords
- Polysaccharide
- Bacteroides
- Biology
- Bacteroides thetaiotaomicron
- Gut flora
- Microbiome
- Microbiology
- Bacteria
- Zero hunger
Funding
- UOUniversity of Queensland
- NNNational Natural Science Foundation of China
- MOMinistry of Science and Technology of the People's Republic of China
- UDUniversidade de MacauAward: SRG2022-00020-FHS
- FPFundo para o Desenvolvimento das Ciências e da TecnologiaAward: 005/2023/SKL
- FDFaculdade de Ciências da Saúde, Universidade de Macau