SARS-CoV-2 drug resistance and therapeutic approaches

In light of the transition of COVID-19 from a pandemic to an endemic phase, there is still a dire need to address challenges associated with drug resistance, particularly among immunocompromised and high-risk populations. This review explores the current state of research on SARS-CoV-2 drug resistance and underscores the ongoing need for effective therapeutic strategies. It critically evaluates existing knowledge on resistance mechanisms and therapeutic options, aiming to consolidate information and highlight areas for future research. By examining the complex interactions between the virus and its host, the review advocates for a multifaceted approach, including combination therapies, targeted drug…

• KD
  Korea Disease Control and Prevention Agency

  Award: 6634-325-320-01
• NR
  National Research Foundation
• MO
  Ministry of Health and Welfare

  Award: HI23C0392
• KH
  Korea Health Industry Development Institute

  Award: HI23C0392
• NR
  National Research Foundation of Korea

  Awards: NRF- 2021R1A2C2006961, NRF-2021R1A2C2006961
• KN
  Korea National Institute of Health
• KC
  Korea Centers for Disease Control and Prevention

  Award: 6634-325-320-01