Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group
University of Modena and Reggio Emilia · Institute of Infection and Immunity · +41 more institutions
Abstract
Approaches, often representing a barrier to achieving the desired editing efficiency and safety. In this review, authored by members of the GenE-HumDi European Cooperation in Science and Technology (COST) Action, we described the plethora of delivery systems available for genome-editing components, including viral and non-viral systems, highlighting their advantages, limitations, and potential application in a clinical setting.
Citation impact
- FWCI
- 26.27
- Percentile
- 100%
- References
- 329
Authors
41- ACAlessia CavazzaCorresponding
University of Modena and Reggio Emilia, Institute of Infection and Immunity, University College London
- FJFrancisco J. Molina-Estévez
Universidad de Granada, Instituto de Investigación Biosanitaria de Granada, Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research
- ÁPÁlvaro Plaza Reyes
Centro Andaluz de Biología Molecular y Medicina Regenerativa
- VRVictor Ronco
Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research
- ANAsma Naseem
Institute of Infection and Immunity, University College London
Topics & keywords
- Genome editing
- Computational biology
- Computer science
- Gene delivery
- Genome
- Genetic enhancement
- Biology
- Action (physics)
- Partnerships for the goals
Funding
- APAlexion Pharmaceuticals
- IInnovationsfonden
- MDMinisterio de Ciencia, Innovación y Universidades
- ECEuropean Cooperation in Science and TechnologyAward: CA21113
- EJEusko JaurlaritzaAward: RYC2018-024397-I
- LLundbeckfondenAward: R396-2022-350
- IBIkerbasque, Basque Foundation for ScienceAward: RF/2019/001
- NNNovo Nordisk
- JAJavna Agencija za Raziskovalno Dejavnost RSAward: J4-4563
- MPMinistarstvo Prosvete, Nauke i Tehnološkog RazvojaAwards: 451-03-66/2024-03/200007, FPU22/03244
- CNCentre National de la Recherche Scientifique
- MDMinisterio de Ciencia e InnovaciónAward: RYC2018-024397-I
- NNNovo Nordisk FondenAwards: NNF21OC0068988, NNF21OC0072031
- JDJunta de AndalucíaAward: PAIDI 2020
- HLH. Lundbeck A/S
- EREuropean Research CouncilAward: 865797 DITSB
- IDInstituto de Salud Carlos IIIAwards: RD21/0017, PI22/01382
- CDConsejería de Salud y Consumo, Junta de Andalucía