From gut to liver: Exploring the crosstalk between gut-liver axis and oxidative stress in metabolic dysfunction-associated steatotic liver disease
Zhejiang Chinese Medical University · The Third Affiliated Hospital of Zhejiang Chinese Medical University · +2 more institutions
Abstract
Non-alcoholic fatty liver disease (NAFLD), now recognized as metabolic dysfunction-associated steatotic liver disease (MASLD), represents a significant and escalating global health challenge. Its prevalence is intricately linked to obesity, insulin resistance, and other components of the metabolic syndrome. As our comprehension of MASLD deepens, it has become evident that this condition extends beyond the liver, embodying a complex, multi-systemic disease with hepatic manifestations that mirror the broader metabolic landscape. This comprehensive review delves into the critical interplay between the gut-liver axis and oxidative stress, elucidating their pivotal roles in the etiology and progression of MASLD.…
Citation impact
- FWCI
- 55.81
- Percentile
- 100%
- References
- 82
Authors
6- MZMi ZhouCorresponding
Zhejiang Chinese Medical University, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Second Affiliated Hospital of Zhejiang University
- JLJianyu Lv
Zhejiang Chinese Medical University, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Second Affiliated Hospital of Zhejiang University
- XCXinli Chen
Zhejiang Chinese Medical University, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Second Affiliated Hospital of Zhejiang University
- YSYujie Shi
Zhejiang Chinese Medical University, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Second Affiliated Hospital of Zhejiang University
- GCGuanqun Chao
Sir Run Run Shaw Hospital
Topics & keywords
- Medicine
- Oxidative stress
- Crosstalk
- Fatty liver
- Disease
- Liver dysfunction
- Liver disease
- Oxidative phosphorylation