reviewPharmaceuticsJan 19, 2025GOLD OA

Resveratrol—A Promising Therapeutic Agent with Problematic Properties

Medical University of Sofia

PubMed
Indexed incrossrefdoajpubmed

Abstract

Resveratrol is a natural polyphenol (stilbenoid), which can be found in grape skin, red wine, blueberries, peanuts and others. The biological properties of resveratrol, in particular antioxidant, anti-inflammatory, anticancer, estrogenic, vasorelaxant and cardioprotective activity, are the main reason for its importance in medicine and pharmacy. Despite all of its advantages, however, there are many problems related to this polyphenolic substance, such as low stability, water insolubility, poor bioavailability and fast metabolism. For this reason, scientists are currently searching for different approaches to dealing with these problematic properties and improving the therapeutic usage of resveratrol. This…

Citation impact

43
total citations
FWCI
40.55
Percentile
100%
References
167
Citations per year

Authors

2

Topics & keywords

Keywords
  • Resveratrol
  • Polyphenol
  • Prodrug
  • Pharmacology
  • Chemistry
  • Bioavailability
  • Antioxidant
  • Drug delivery
UN Sustainable Development Goals
  • Clean water and sanitation
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Funding