Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques
Gulf Medical University · Ajman University · +1 more institution
Abstract
Nanosuspensions (NS), with their submicron particle sizes and unique physicochemical properties, provide a versatile solution for enhancing the administration of medications that are not highly soluble in water or lipids. This review highlights recent advancements, future prospects, and challenges in NS-based drug delivery, particularly for oral, ocular, transdermal, pulmonary, and parenteral routes. The conversion of oral NS into powders, pellets, granules, tablets, and capsules, and their incorporation into film dosage forms to address stability concerns is thoroughly reviewed. This article summarizes key stabilizers, polymers, surfactants, and excipients used in NS formulations, along with ongoing clinical…
Citation impact
- FWCI
- 32.23
- Percentile
- 100%
- References
- 289
Authors
5Topics & keywords
- Transdermal
- Nanotechnology
- Bioavailability
- Drug
- Drug delivery
- Commercialization
- Pharmacology
- Biochemical engineering