reviewPharmaceuticsJan 19, 2025GOLD OA

Nanosuspension Innovations: Expanding Horizons in Drug Delivery Techniques

Gulf Medical University · Ajman University · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Nanosuspensions (NS), with their submicron particle sizes and unique physicochemical properties, provide a versatile solution for enhancing the administration of medications that are not highly soluble in water or lipids. This review highlights recent advancements, future prospects, and challenges in NS-based drug delivery, particularly for oral, ocular, transdermal, pulmonary, and parenteral routes. The conversion of oral NS into powders, pellets, granules, tablets, and capsules, and their incorporation into film dosage forms to address stability concerns is thoroughly reviewed. This article summarizes key stabilizers, polymers, surfactants, and excipients used in NS formulations, along with ongoing clinical…

Citation impact

53
total citations
FWCI
32.23
Percentile
100%
References
289
Citations per year

Authors

5

Topics & keywords

Keywords
  • Transdermal
  • Nanotechnology
  • Bioavailability
  • Drug
  • Drug delivery
  • Commercialization
  • Pharmacology
  • Biochemical engineering
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