Selenium and Selenoproteins: Mechanisms, Health Functions, and Emerging Applications

Selenium (Se) is an essential trace element crucial for human health that primarily functions as an immunonutrient. It is incorporated into polypeptides such as selenocysteine (SeC) and selenomethionine (SeMet), two key amino acids involved in various biochemical processes. All living organisms can convert inorganic Se into biologically active organic forms, with SeMet being the predominant form and a precursor for SeC production in humans and animals. The human genome encodes 25 selenoprotein genes, which incorporate low-molecular-weight Se compounds in the form of SeC. Organic Se, especially in the form of selenoproteins, is more efficiently absorbed than inorganic Se, driving the demand for…

• NN
  National Natural Science Foundation of China

  Awards: 31960075, 21602196
• TT
  Ten Thousand Talent Plans for Young Top-notch Talents of Yunnan Province

  Award: YNWR-QNB J-2020-178