The role of interleukin-17 in inflammation-related cancers

Emerging evidence indicates a correlation between inflammation and the development and progression of cancer. Among the various inflammatory signals, interleukin-17 (IL-17) family cytokines serve as a critical link between inflammation and cancer. IL-17 is a highly versatile pro-inflammatory cytokine that plays a pivotal role in host defense, tissue repair, the pathogenesis of inflammatory diseases, and cancer progression. During the early stages of tumorigenesis, IL-17 signaling directly promotes the proliferation of tumor cells. Conversely, IL-17 has been shown to exhibit antitumor immunity in several models of grafted subcutaneous tumors. Additionally, dynamic changes in the microbiome can influence the…

• TC
  Traditional Chinese Medicine Bureau of Guangdong Province

  Award: 202305041559305920
• FS
  Foshan Science and Technology Bureau

  Award: 2220001005369, 2320001007101, 2320001007336
• BA
  Basic and Applied Basic Research Foundation of Guangdong Province

  Award: 2022A1515110809