articleAdvanced Functional MaterialsJan 23, 2025BRONZE OA

Honeysuckle‐Derived Carbon Dots With Robust Catalytic and Pharmacological Activities for Mitigating Lung Inflammation by Inhibition of Caspase11/GSDMD‐Dependent Pyroptosis

ZDZhichao DengYZYujie ZhangRLRunqing LiYZYuan‐Yuan ZhuCXChenxi Xu

First Affiliated Hospital of Xi'an Jiaotong University · Xi'an Jiaotong University

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Abstract

Abstract The catalytic activity of carbon dots (CDs) has generated significant interest regarding their potential applications within the biomedical field. However, the structure‐activity relationship of CDs and their pharmacological mechanisms in disease treatment have yet to be comprehensively elucidated. In this study, two distinct types of CDs exhibiting superoxide dismutase (SOD)‐like enzymatic activities are synthesized through hydrothermal (Hy‐CDs) and carbonization (Ca‐CDs) methods, utilizing Honeysuckle as the common carbon material precursor. Through comparative analysis, surface group modifications, and theoretical calculations, it is determined that the SOD‐like enzymatic activity of CDs primarily…

Citation impact

42
total citations
FWCI
17.04
Percentile
100%
References
44
Citations per year

Authors

13

Topics & keywords

Topics
Keywords
  • Pyroptosis
  • Materials science
  • Nanotechnology
  • Inflammation
  • Honeysuckle
  • Medicine
  • Immunology
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