articleJournal of NanobiotechnologyJan 27, 2025GOLD OA

An antibacterial, antioxidant and hemostatic hydrogel accelerates infectious wound healing

Army Medical University · Xinqiao Hospital · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Hydrogel drug-delivery system that can effectively load antibacterial drugs, realize the in-situ drug release in the microenvironment of wound infection to promote wound healing. In this study, a multifunctional hydrogel drug delivery system (HA@TA-Okra) was constructed through the integration of hyaluronic acid methacrylate (HAMA) matrix with tannic acid (TA) and okra extract. The composition and structural characteristics of HA@TA-Okra system and its unique advantages in the treatment of diverse wounds were systematically evaluated. TA, due to its unique chemical structure, is able to anchor within the HAMA network through interactions and cross-linking, conferring exceptional mechanical strength and…

Citation impact

42
total citations
FWCI
32.41
Percentile
100%
References
57
Citations per year

Authors

10

Topics & keywords

Keywords
  • Wound healing
  • Antioxidant
  • Tannic acid
  • In vivo
  • Chemistry
  • Drug delivery
  • Self-healing hydrogels
  • Pharmacology
UN Sustainable Development Goals
  • Good health and well-being
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