Histone lactylation-driven B7-H3 expression promotes tumor immune evasion
Huazhong University of Science and Technology · Tongji Hospital
Indexed incrossrefdoajpubmed
Abstract
This study uncovers a novel mechanism by which lactate modulates the immune microenvironment through the glycolysis pathway and B7-H3 expression, providing new avenues for lactate metabolism-targeted tumor immunotherapy.
Citation impact
71
total citations
- FWCI
- 55.75
- Percentile
- 100%
- References
- 70
Citations per year
Authors
10Topics & keywords
Topics
Keywords
- Histone H3
- Immune system
- Evasion (ethics)
- Histone
- Cancer research
- Cell biology
- Chemistry
- Biology
UN Sustainable Development Goals
- Zero hunger
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