Applications of liposomes and lipid nanoparticles in cancer therapy: current advances and prospects
Central South University · Third Xiangya Hospital · +1 more institution
Abstract
Liposomes and lipid nanoparticles are common lipid-based drug delivery systems and play important roles in cancer treatment and vaccine manufacture. Although significant progress has been made with these lipid-based nanocarriers in recent years, efficient clinical translation of active targeted liposomal nanocarriers remains extremely challenging. In this review, we focus on targeted liposomes, stimuli-responsive strategy and combined therapy in cancer treatment. We also summarize advances of liposome and lipid nanoparticle applications in nucleic acid delivery and tumor vaccination. In addition, we discuss limitations and challenges in the clinical translation of these lipid nanomaterials and make…
Citation impact
- FWCI
- 43.92
- Percentile
- 100%
- References
- 205
Authors
4- ZCZhe ChengCorresponding
Central South University, Third Xiangya Hospital
- HHHuichao Huang
Central South University, Xiangya Hospital Central South University
- MYMeilong Yin
Central South University, Third Xiangya Hospital
- HLHuaizheng Liu
Central South University, Third Xiangya Hospital
Topics & keywords
- Liposome
- Current (fluid)
- Cancer
- Nanotechnology
- Cancer therapy
- Nanoparticle
- Medicine
- Materials science
- Good health and well-being