tidk: a toolkit to rapidly identify telomeric repeats from genomic datasets
Anglia Ruskin University · Wellcome Sanger Institute
Abstract
SUMMARY: "tidk" (short for telomere identification toolkit) uses a simple, fast algorithm to scan long DNA reads for the presence of short tandemly repeated DNA in runs, and to aggregate them based on canonical DNA string representation. These are telomeric repeat candidates. Our algorithm is shown to be accurate in genomes for which the telomeric repeat unit is known and is tested across a wide variety of newly assembled genomes to uncover new telomeric repeat units. Tools are provided to identify telomeric repeats de novo, scan genomes for known telomeric repeats, and to visualize telomeric repeats on the assembly. "tidk" is implemented in Rust and is available as a command line tool which can be compiled…
Citation impact
- FWCI
- 61.62
- Percentile
- 100%
- References
- 18
Authors
3Topics & keywords
- Genome
- Computer science
- Source code
- String (physics)
- Toolchain
- Computational biology
- Telomere
- Biology