Testicular Germ Cell Tumors
Johns Hopkins University · Johns Hopkins Medicine · +4 more institutions
Abstract
Importance: Testicular cancer is the most common solid malignancy among males aged 15 to 40 years in the US, with approximately 10 000 new cases diagnosed each year. Between 90% and 95% of testicular cancers are germ cell tumors (GCTs). Observations: The mean age at diagnosis for testicular cancer is 33 years. GCTs are categorized as seminomas and nonseminomatous GCTs (NSGCTs) based on their embryonic origins and path of differentiation. Risk factors include cryptorchidism, family history of testicular cancer, gonadal dysgenesis, infertility, cannabis use, and genetic conditions such as Klinefelter syndrome. The most common presenting symptom of testicular cancer is a painless testicular mass. History,…
Citation impact
- FWCI
- 90.57
- Percentile
- 100%
- References
- 119
Authors
5- NSNirmish SinglaCorresponding
Johns Hopkins University, Johns Hopkins Medicine
- ABAditya Bagrodia
University of California San Diego, The University of Texas Southwestern Medical Center
- EBEzra Baraban
Johns Hopkins University, Johns Hopkins Medicine
- CDChristian D. Fankhauser
University of Lucerne, Luzerner Kantonsspital
- YGYasser Ged
Johns Hopkins University, Johns Hopkins Medicine
Topics & keywords
- Medicine
- Testicular cancer
- Human chorionic gonadotropin
- Germ cell tumors
- Malignancy
- Klinefelter syndrome
- Cancer
- Seminoma
- Good health and well-being