Mechanical signatures in cancer metastasis
University College London · Capital Medical University · +4 more institutions
Indexed incrossrefpubmed
Abstract
The cancer metastatic cascade includes a series of mechanical barrier-crossing events, involving the physical movement of cancer cells from their primary location to a distant organ. This review describes the physical changes that influence tumour proliferation, progression, and metastasis. We identify potential mechanical signatures at every step of the metastatic cascade and discuss some latest mechanobiology-based therapeutic interventions to highlight the importance of interdisciplinary approaches in cancer diagnosis and treatment.
Citation impact
53
total citations
- FWCI
- 46.43
- Percentile
- 100%
- References
- 247
Citations per year
Authors
9Topics & keywords
Topics
Keywords
- Mechanobiology
- Metastasis
- Cancer
- Medicine
- Cancer metastasis
- Oncology
- Internal medicine
- Anatomy
UN Sustainable Development Goals
- Good health and well-being
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