An Update of Fungal Endophyte Diversity and Strategies for Augmenting Therapeutic Potential of their Potent Metabolites: Recent Advancement

Prajapati, Chandrabhan; Nand, Sachchida; Singh, Santosh Kumar; Chopade, Balu A.; Singh, Yashveer; Singh, Santosh Kumar; Haque, Shafiul; Prieto, Miguel A.; Ashraf, Ghulam Md

doi:10.1007/s12010-024-05098-9

reviewApplied Biochemistry and BiotechnologyFeb 5, 2025HYBRID OA

An Update of Fungal Endophyte Diversity and Strategies for Augmenting Therapeutic Potential of their Potent Metabolites: Recent Advancement

CPChandrabhan Prajapati SNSachchida Nand SKSantosh Kumar Singh BABalu A. ChopadeYSYashveer Singh

Institute of Medical Sciences · Banaras Hindu University · +5 more institutions

PubMed

Indexed incrossrefpubmed

Abstract

Endophytic fungi represent a significant renewable resource for the discovery of pharmaceutically important compounds, offering substantial potential for new drug development. Their ability to address the growing issue of drug resistance has drawn attention from researchers seeking novel, nature-derived lead molecules that can be produced on a large scale to meet global demand. Recent advancements in genomics, metabolomics, bioinformatics, and improved cultivation techniques have significantly aided the identification and characterization of fungal endophytes and their metabolites. Current estimates suggest there are approximately 1.20 million fungal endophytes globally, yet only around 16% (190,000) have been…

Citation impact

61

total citations

FWCI: 68.57
Percentile: 100%
References: 396

Citations per year

Authors

9

Topics & keywords

Topics

Keywords

Biology
Biotechnology
Metabolomics
Computational biology
Drug discovery
Plant use of endophytic fungi in defense
Identification (biology)
Endophyte

No related works found for this paper.