reviewAccounts of Chemical ResearchFeb 5, 2025Closed access

Near-Infrared-II Fluorescent Probes for Analytical Applications: From In Vitro Detection to In Vivo Imaging Monitoring

Anhui University of Traditional Chinese Medicine · Advanced Research Institute · +5 more institutions

PubMed
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Abstract

ConspectusBiomarkers play a vital role in the regulation of life processes, especially in predicting the occurrence and development of diseases. For the early diagnosis and precise treatment of diseases, it has become necessary and significant to detect biomarkers with sensitivity, accuracy, simplicity, convenience, and even visualization. Fluorescent-probe-based techniques have been recognized as one of the most powerful tools for the sensitive detection and real time imaging of biomarkers in biological samples. However, traditional optical probes, mainly including the visible probes (400–700 nm) and the near-infrared I (NIR-I, 700–900 nm) probes, suffer from low sensitivity, poor resolution, strong…

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54
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100%
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Authors

5

Topics & keywords

Keywords
  • Fluorescence
  • In vivo
  • Infrared
  • In vitro
  • Chemistry
  • Biophysics
  • Nanotechnology
  • Materials science
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