articleNew England Journal of MedicineFeb 5, 2025GREEN OA

Efficacy of Zenocutuzumab in NRG1 Fusion–Positive Cancer

Memorial Sloan Kettering Cancer Center · Cornell University · +30 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Background

fusion-positive solid tumors are unclear.

Methods

fusion-positive cancer involving any tumor type to receive zenocutuzumab at a dose of 750 mg intravenously every 2 weeks. The primary end point was overall response (complete or partial response) according to investigator assessment. Secondary end points included duration of response, progression-free survival, and safety.

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