Engineered Living Systems Based on Gelatin: Design, Manufacturing, and Applications
Brigham and Women's Hospital · Harvard University · +2 more institutions
Abstract
Engineered living systems (ELSs) represent purpose-driven assemblies of living components, encompassing cells, biomaterials, and active agents, intricately designed to fulfill diverse biomedical applications. Gelatin and its derivatives have been used extensively in ELSs owing to their mature translational pathways, favorable biological properties, and adjustable physicochemical characteristics. This review explores the intersection of gelatin and its derivatives with fabrication techniques, offering a comprehensive examination of their synergistic potential in creating ELSs for various applications in biomedicine. It offers a deep dive into gelatin, including its structures and production, sources,…
Citation impact
- FWCI
- 23.13
- Percentile
- 100%
- References
- 419
Authors
12- ZWZhenwu Wang
Brigham and Women's Hospital, Harvard University
- ZLZeng Lin
Brigham and Women's Hospital, Harvard University
- XMXuan Mei
Brigham and Women's Hospital, Harvard University
- LCLing Cai
Brigham and Women's Hospital, Harvard University
- KLKo‐Chih Lin
Brigham and Women's Hospital, Harvard University
Topics & keywords
- Materials science
- Gelatin
- Nanotechnology
- Manufacturing engineering
- Systems engineering
- Process engineering
- Engineering
- Organic chemistry
Funding
- NSNational Science FoundationAwards: CISE‐IIS‐2225698, CBET‐EBMS‐1936105
- FFFoundation for the National Institutes of HealthAwards: UH3TR003274, R21EB030257, R01HL153857, R01HL165176, R01EB028143, R01GM134036, UH3TR003274‐S1, R21HL168656, R56EB034702, R01HL166522, R01CA282451
- CZChan Zuckerberg InitiativeAward: 2022‐316712