reviewPharmaceuticsFeb 7, 2025GOLD OA

Hydrogels and Nanogels: Pioneering the Future of Advanced Drug Delivery Systems

EJErnesto J. Delgado-PujolGMGuillermo MartínezDCDavid Casado-JuradoJVJuan VázquezJLJesús León-Barberena

Universidad de Sevilla

PubMed
Indexed incrossrefdoajpubmed

Abstract

Conventional drug delivery approaches, including tablets and capsules, often suffer from reduced therapeutic effectiveness, largely attributed to inadequate bioavailability and difficulties in ensuring patient adherence. These challenges have driven the development of advanced drug delivery systems (DDS), with hydrogels and especially nanogels emerging as promising materials to overcome these limitations. Hydrogels, with their biocompatibility, high water content, and stimuli-responsive properties, provide controlled and targeted drug release. This review explores the evolution, properties, and classifications of hydrogels versus nanogels and their applications in drug delivery, detailing synthesis methods,…

Citation impact

144
total citations
FWCI
64.67
Percentile
100%
References
237
Citations per year

Authors

9

Topics & keywords

Topics
Keywords
  • Self-healing hydrogels
  • Drug delivery
  • Nanotechnology
  • Biocompatibility
  • Nanogel
  • Materials science
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