reviewCell Death DiscoveryFeb 10, 2025GOLD OA

Insights on the crosstalk among different cell death mechanisms

Ain Shams University

PubMed
Indexed incrossrefdoajpubmed

Abstract

The phenomenon of cell death has garnered significant scientific attention in recent years, emerging as a pivotal area of research. Recently, novel modalities of cellular death and the intricate interplay between them have been unveiled, offering insights into the pathogenesis of various diseases. This comprehensive review delves into the intricate molecular mechanisms, inducers, and inhibitors of the underlying prevalent forms of cell death, including apoptosis, autophagy, ferroptosis, necroptosis, mitophagy, and pyroptosis. Moreover, it elucidates the crosstalk and interconnection among the key pathways or molecular entities associated with these pathways, thereby paving the way for the identification of…

Citation impact

83
total citations
FWCI
94.81
Percentile
100%
References
251
Citations per year

Authors

4

Topics & keywords

Keywords
  • Necroptosis
  • Pyroptosis
  • Autophagy
  • Crosstalk
  • Programmed cell death
  • Mitophagy
  • Biology
  • Neuroscience
UN Sustainable Development Goals
  • Good health and well-being
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