Cumulative Incidence of Mortality Associated with Cardiovascular–Kidney–Metabolic (CKM) Syndrome

Key Points Cardiovascular–kidney–metabolic (CKM) syndrome stages 1–4 were associated with a graded risk of cardiovascular mortality in a nationally representative sample of US adults. Risk was similar between stages 0 and 1, suggesting that stage 1 represents a prime opportunity for prevention and risk mitigation. CKM staging is specific to cardiovascular mortality, given lack of a strong association with either noncardiovascular or cancer mortality. Background It is imperative to critically evaluate the prognostic implications of cardiovascular–kidney–metabolic (CKM) syndrome staging to inform clinical practice. The primary aims of this study were to define the risk of mortality associated with each CKM…

• NH
  National Heart, Lung, and Blood Institute

  Award: R38HL143584