Multiple roles of NAC transcription factors in plant development and stress responses

NAC (NAM, ATAF1/2, and CUC2) transcription factors (TFs) are a family of plant-specific TFs that play crucial roles in various aspects of plant development and stress responses. Here, we provide an in-depth review of the structural characteristics, regulatory mechanisms, and functional roles of NACs in different plant species. One of the key features of NACs is their ability to regulate gene expression through a variety of mechanisms, including binding to DNA sequences in the promoter regions of target genes, interacting with other TFs, and modulating chromatin structure. We discuss these mechanisms in detail, providing insights into the complex regulatory networks that govern the activity of NACs. We explore…

• NN
  National Natural Science Foundation of China

  Awards: U21A20207, 31821005, 31930080, 32272041
• NS
  Natural Science Foundation of Hubei Province

  Award: 2024AFB714
• EF
  Earmarked Fund for China Agriculture Research System

  Awards: CARS-01, CARS‐01
• FR
  Fundamental Research Funds for the Central Universities

  Award: 2662022SKQD003