articleGut MicrobesFeb 16, 2025GOLD OA

Microbiota-derived IPA alleviates intestinal mucosal inflammation through upregulating Th1/Th17 cell apoptosis in inflammatory bowel disease

HGHan GaoMSMingming SunLALi AiQGQiaoyan GuDKDengfeng Kang

Tongji University · Shanghai Tenth People's Hospital · +6 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

T cells conferred resistance to IPA-induced Th1/Th17 cell apoptosis. Therefore, these findings identify a previously unrecognized pathway by which IPA modulates intestinal inflammation and provide a promising avenue for the treatment of IBD.

Citation impact

70
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FWCI
43.68
Percentile
100%
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57
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Authors

12

Topics & keywords

Topics
Keywords
  • Inflammatory bowel disease
  • Inflammation
  • Apoptosis
  • Biology
  • Disease
  • Immunology
  • Inflammatory Bowel Diseases
  • Gut flora
UN Sustainable Development Goals
  • Zero hunger
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