reviewPhysiological ReviewsFeb 18, 2025GREEN OA

The pathogenesis of cerebral small vessel disease and vascular cognitive impairment

HSHugh S. MarkusAJAnne Joutel

University of Cambridge · Université Paris Cité · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Cerebral small vessel disease (cSVD) is the broadly accepted term nowadays to designate a heterogeneous group of diseases caused by in situ damage of small brain vessels commonly related to aging, hypertension, or genetic factors. Cardinal neuroimaging features include small (

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61
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Topics & keywords

Topics
Keywords
  • Hyperintensity
  • Neuroscience
  • Neuroimaging
  • Disease
  • Cognition
  • Medicine
  • Cognitive impairment
  • Pathology
UN Sustainable Development Goals
  • Good health and well-being
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