reviewComputers in Biology and MedicineFeb 19, 2025HYBRID OA

Utilizing machine learning for predicting drug release from polymeric drug delivery systems

Tehran University of Medical Sciences · Mazandaran University of Medical Sciences · +5 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Polymeric drug delivery systems (PDDS) play a crucial role in controlled drug release, providing improved therapeutic outcomes. However, formulating PDDS and predicting their release profiles remain challenging due to their complex structures and the numerous variables that influence their behavior. Traditional mathematical and empirical prediction methods are limited in capturing these complexities. Recent studies have unveiled the potential of Machine Learning (ML) in revolutionizing drug delivery, particularly in formulating complex PDDS. This article provides an overview of the significant and fundamental principles of various ML strategies in estimating PDDS drug release behavior. Our focus extends to the…

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