Progress in Drug Delivery Systems Based on Nanoparticles for Improved Glioblastoma Therapy: Addressing Challenges and Investigating Opportunities
Wayne State University · The Barbara Ann Karmanos Cancer Institute · +1 more institution
Abstract
Glioblastoma multiforme (GBM) is a highly malignant brain tumor that has a bleak outlook despite existing treatments such as surgery, radiation, and chemotherapy. The utilization of nanoparticles for drug delivery presents a promising method by which to improve the effectiveness of treatment while reducing the harmful effects on the entire body. This review examines the application of nanoparticles in the treatment of GBM, focusing on different types of nanoparticles, including lipid-based, polymeric, metallic, and those under development. Every variety is analyzed for its distinct characteristics and therapeutic capacity. Lipid-based nanoparticles, such as liposomes and solid lipid nanoparticles, enhance the…
Citation impact
- FWCI
- 24.74
- Percentile
- 100%
- References
- 193
Authors
4- MAMd. Ataur RahmanCorresponding
Wayne State University, The Barbara Ann Karmanos Cancer Institute
- MJMaroua Jalouli
Imam Mohammad ibn Saud Islamic University
- MKMahesh Kumar Yadab
Wayne State University, The Barbara Ann Karmanos Cancer Institute
- MAMohammed Al‐Zharani
Imam Mohammad ibn Saud Islamic University
Topics & keywords
- Glioblastoma
- Drug delivery
- Drug
- Medicine
- Nanotechnology
- Computer science
- Pharmacology
- Materials science