Treatment of Osteoporosis and Osteoarthritis in the Oldest Old

Osteoporosis and osteoarthritis are key diseases of musculoskeletal ageing and are increasing in prevalence and burden with the progressively ageing population worldwide. These conditions are thus particularly common in 'the oldest old', and there are complexities of managing them within the context of extensive multimorbidity, physical and mental disability, and polypharmacy, the rates for all of which are high in this population. In this narrative review, we explore the epidemiology of osteoporosis and osteoarthritis in the oldest old before examining trials and real-world data relating to the pharmacological treatment of these diseases in older adults, including anti-resorptives and bone-forming agents in…

• KS
  King Saud University
• MR
  Medical Research Council

  Awards: MR/J000094/1, MC_PC_21003, MC_PC_21000, MC_PC_21001, MC_UU_12011/2, MC_UU_12011/1, MC_PC_21022