articleTheranosticsFeb 10, 2025GOLD OA

Targeting platinum-resistant ovarian cancer by disrupting histone and RAD51 lactylation

Qilu Hospital of Shandong University · Uppsala University

PubMed
Indexed incrossrefdoajpubmed

Abstract

Our study demonstrated the essential role of histone and RAD51 lactylation in HR repair and platinum resistance. It also identified a potential therapeutic strategy to overcome platinum resistance and improve prognosis in ovarian cancer.

Citation impact

50
total citations
FWCI
30.81
Percentile
100%
References
0
Citations per year

Authors

14

Topics & keywords

Keywords
  • Ovarian cancer
  • Histone
  • Cancer research
  • RAD51
  • Platinum
  • Medicine
  • Internal medicine
  • Oncology
UN Sustainable Development Goals
  • Zero hunger
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