articleTalanta OpenFeb 20, 2025GOLD OA

Ultrafast microwave-assisted green synthesis of nitrogen-doped carbon dots as turn-off fluorescent nanosensors for determination of the anticancer nintedanib: Monitoring of environmental water samples

Kafrelsheikh University · Mansoura University · +1 more institution

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Abstract

• This study presents the first spectrofluorimetric method for nintedanib analysis. • Ultrafast green synthesis of N-CQDs was performed in less than one minute. • Analysis of nintedanib relies on the quantitative quenching of N-CQDs' fluorescence. • The detection limit reaches 0.14 μg/mL in environmental water samples. • The method's greenness and practicality were demonstrated using different metrics. This study unveils a swift and sustainable approach for the synthesis of nitrogen-doped carbon quantum dots (N-CQDs) from radish leaves and urea, conducted by microwave assistance within only 50 seconds, showcasing remarkable efficiency. Comprehensive characterization confirmed the distinctive optical properties…

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