Click Analytical Chemistry Index as a novel concept and framework, supported with open source software to assess analytical methods

• A new assessment tool supported by open-source software for method evaluation. • CACI emphasizes simplicity, efficiency, and practical aspects in chemical analysis. • This tool provides an objective metric for comparing analytical methods. • Case studies demonstrating real-world applications are discussed. • CACI bridges the gap between analytical performance and practical attributes. Click analytical chemistry (CAC) is a novel approach inspired by the principles of click chemistry, emphasizing simplicity, efficiency, and reliability. While click chemistry revolutionized synthetic methods, CAC aims to enhance chemical analysis by providing a framework for method assessment from a different perspective,…