Biodegradation of polyhydroxyalkanoates: current state and future prospects

Polyhydroxyalkanoates (PHAs) are biobased and biodegradable polymers that offer a sustainable alternative to conventional plastics, addressing the escalating concerns over plastic pollution. While their environmental advantages are well-documented, the efficient degradation of PHAs in natural and engineered environments remains a critical component of their lifecycle. This review provides a comprehensive overview of PHA-degrading bacteria isolated from diverse ecosystems and highlights the pivotal role of PHA depolymerases in achieving PHA circularity. Microbial adaptation to diverse environmental conditions, such as extreme temperatures, salinity, and pH, significantly influences enzymes properties, including…