Inflammation in cancer: therapeutic opportunities from new insights

As one part of the innate immune response to external stimuli, chronic inflammation increases the risk of various cancers, and tumor-promoting inflammation is considered one of the enabling characteristics of cancer development. Recently, there has been growing evidence on the role of anti-inflammation therapy in cancer prevention and treatment. And researchers have already achieved several noteworthy outcomes. In the review, we explored the underlying mechanisms by which inflammation affects the occurrence and development of cancer. The pro- or anti-tumor effects of these inflammatory factors such as interleukin, interferon, chemokine, inflammasome, and extracellular matrix are discussed. Since FDA-approved…

• NN
  National Natural Science Foundation of China

  Awards: 82303891, 82473228, 82472998, 82203594, 82303119
• ED
  Education Department of Henan Province

  Award: 23ZX007
• SA
  Science and Technology Department of Henan Province

  Awards: 232102310195, 242102311082