Current strategies against multidrug-resistant Staphylococcus aureus and advances toward future therapy

Antimicrobial resistance (AMR) has emerged as a formidable challenge in the treatment of infectious diseases, posing significant risks to global health. This issue is particularly with Staphylococcus aureus , a bacterium that can become multidrug-resistant (MDR), leading to severe complications and systemic infections due to their complex characteristics and diverse virulence factors. These new developments of AMR in S. aureus affected the scientific community in discovering the next generation of antibiotics, in which only two classes of antibiotics for clinical use have been introduced in the past two decades. This stagnation highlights the urgency of addressing AMR and the increasing difficulty in combating…