articleMaterials Today BioFeb 25, 2025GOLD OA

Exosome isolation and characterization for advanced diagnostic and therapeutic applications

Dr. Reddy's Laboratories (India) · Maulana Abul Kalam Azad University of Technology, West Bengal · +8 more institutions

PubMed
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Abstract

Advancements in exosome isolation technologies are pivotal for transforming personalized medicine and enhancing clinical diagnostics. Exosomes, small extracellular vesicles with diameters ranging between 30 and 150 nm, are secreted into bodily fluids by a variety of cells and play essential roles in intercellular communication. These vesicles facilitate the transfer of nucleic acids, lipids, and proteins, affecting a wide range of biological and pathological processes. Given their importance in disease diagnostics, therapy, and as biomarkers, there has been a surge in developing methods to isolate them from fluids such as urine, saliva, blood, and cerebrospinal fluid. While traditional isolation techniques…

Citation impact

57
total citations
FWCI
37.35
Percentile
100%
References
215
Citations per year

Authors

11

Topics & keywords

Keywords
  • Isolation (microbiology)
  • Exosome
  • Characterization (materials science)
  • Computational biology
  • Computer science
  • Microvesicles
  • Biology
  • Nanotechnology
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