reviewLangmuirMar 3, 2025Closed access

Antifouling Polymer Coatings for Bioactive Surfaces

Soochow University · Ingenierie des Materiaux polymeres · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Bioactive surfaces play a pivotal role in biomedical applications by enabling precise biological interactions through immobilized functional molecules. However, their performance is often hindered by nonspecific protein adsorption and cell adhesion. Antifouling polymer coatings have emerged as an effective solution, creating hydration barriers to preserve functionality and reduce biofouling. This review provides an overview of the recent advances in the development of antifouling polymer coatings for bioactive surfaces, with particular focus on nonionic polymers, such as polyethylene glycol (PEG), and zwitterionic polymers like poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC). Among them, zwitterionic…

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