3D printed porous magnesium metal scaffolds with bioactive coating for bone defect repair: enhancing angiogenesis and osteogenesis
Chinese PLA General Hospital · Shanghai Jiao Tong University · +6 more institutions
Abstract
In orthopedics, the effective treatment of bone defects remains a major challenge. Magnesium (Mg) metals, with their excellent biocompatibility and favorable osteoconductivity, osteoinductivity, and osseointegration properties, hold great promise for addressing this issue. However, the rapid degradation rate of magnesium restricts its clinical application. In this study, a triply periodic minimal surface (TPMS)-structured porous magnesium alloy (Mg-Nd-Zn-Zr, JDBM) was fabricated using the laser powder bed fusion (LPBF) process. Strontium-doped octacalcium phosphate (SrOCP) and strontium hydrogen phosphate biphasic composite coatings were applied to the surface of the scaffolds. The results showed that the TPMS…
Citation impact
- FWCI
- 24.06
- Percentile
- 100%
- References
- 62
Authors
23Topics & keywords
- Angiogenesis
- Magnesium
- Biomedical engineering
- Chemistry
- Bone healing
- 3d printed
- Porosity
- Dentistry