reviewProgress in Retinal and Eye ResearchMar 4, 2025HYBRID OA

Oculomics: Current concepts and evidence

Centre for Eye Research Australia · Hong Kong Polytechnic University · +22 more institutions

PubMed
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Abstract

The eye provides novel insights into general health, as well as pathogenesis and development of systemic diseases. In the past decade, growing evidence has demonstrated that the eye's structure and function mirror multiple systemic health conditions, especially in cardiovascular diseases, neurodegenerative disorders, and kidney impairments. This has given rise to the field of oculomics-the application of ophthalmic biomarkers to understand mechanisms, detect and predict disease. The development of this field has been accelerated by three major advances: 1) the availability and widespread clinical adoption of high-resolution and non-invasive ophthalmic imaging ("hardware"); 2) the availability of large studies…

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