reviewiMetaFeb 1, 2025GOLD OA

Gut–X axis

LXLin XuYZYu ZhangXLXueyan LiCLChangzhou LiHHHui Hu

The First People's Hospital of Shunde · Southern Medical University · +9 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Recent advances in understanding the modulatory functions of gut and gut microbiota on human diseases facilitated our focused attention on the contribution of the gut to the pathophysiological alterations of many extraintestinal organs, including the liver, heart, brain, lungs, kidneys, bone, skin, reproductive, and endocrine systems. In this review, we applied the "gut-X axis" concept to describe the linkages between the gut and other organs and discussed the latest findings related to the "gut-X axis," including the underlying modulatory mechanisms and potential clinical intervention strategies.

Citation impact

83
total citations
FWCI
115.85
Percentile
100%
References
698
Citations per year

Authors

25

Topics & keywords

Topics
Keywords
  • Geology
  • Computer science
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