articleJournal of the American Society of NephrologyMar 5, 2025Closed access

Global Burden of the Key Components of Cardiovascular-Kidney-Metabolic Syndrome

ZXZhaomin XieCYChaolun YuQCQingmei CuiXZXirui ZhaoJZJuncheng Zhuang

Guangdong Academy of Medical Sciences · Guangdong Provincial People's Hospital · +3 more institutions

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Abstract

Key Points Ischemic heart disease and stroke were the leading contributors to the cardiovascular-kidney-metabolic (CKM) syndrome–related burden in 2021. Regions with a middle sociodemographic index, such as Southeast Asia and the Western Pacific, faced the highest burden. The burden of CKM syndrome is substantial and projected to rise through 2046, highlighting the need for targeted interventions. Background Cardiovascular-kidney-metabolic (CKM) syndrome highlights the interconnected nature of metabolic diseases, CKD, and cardiovascular diseases, representing a significant and growing public health burden. This study aimed to quantify the global burden of CKM syndrome by examining its key components, including…

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55
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100%
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Authors

8

Topics & keywords

Topics
Keywords
  • Metabolic syndrome
  • Key (lock)
  • Medicine
  • Intensive care medicine
  • Kidney
  • Internal medicine
  • Cardiology
  • Computer science
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