Botanical Flavonoids: Efficacy, Absorption, Metabolism and Advanced Pharmaceutical Technology for Improving Bioavailability
Chinese Academy of Sciences · Lushan Botanical Garden
Abstract
Flavonoids represent a class of natural plant secondary metabolites with multiple activities including antioxidant, antitumor, anti-inflammatory, and antimicrobial properties. However, due to their structural characteristics, they often exhibit low bioavailability in vivo. In this review, we focus on the in vivo study of flavonoids, particularly the effects of gut microbiome on flavonoids, including common modifications such as methylation, acetylation, and dehydroxylation, etc. These modifications aim to change the structural characteristics of the original substances to enhance absorption and bioavailability. In order to improve the bioavailability of flavonoids, we discuss two feasible methods, namely…
Citation impact
- FWCI
- 56.48
- Percentile
- 100%
- References
- 252
Authors
4- LHLei Hu
Chinese Academy of Sciences, Lushan Botanical Garden
- YLYiqing Luo
Chinese Academy of Sciences, Lushan Botanical Garden
- JYJiaxin Yang
Chinese Academy of Sciences, Lushan Botanical Garden
- CCChunsong ChengCorresponding
Chinese Academy of Sciences, Lushan Botanical Garden
Topics & keywords
- Bioavailability
- Chemistry
- In vivo
- Absorption (acoustics)
- Antioxidant
- Antimicrobial
- Microbiome
- Pharmacology