Advances in the diagnosis of early biomarkers for acute kidney injury: a literature review
University of Electronic Science and Technology of China
Abstract
Acute kidney injury (AKI) is a critical condition with diverse manifestations and variable outcomes. Its diagnosis traditionally relies on delayed indicators such as serum creatinine and urine output, making early detection challenging. Early identification is essential to improving patient outcomes, driving the need for novel biomarkers. Recent advancements have identified promising biomarkers across various biological processes. Tubular injury markers, including neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), N-acetyl-β-D-glucosaminidase (NAG), and liver-type fatty acid-binding protein (L-FABP), offer insights into early tubular damage. Inflammatory and repair-associated…
Citation impact
- FWCI
- 61.99
- Percentile
- 100%
- References
- 129
Authors
5- HYHongsha YangCorresponding
University of Electronic Science and Technology of China
- YCYanqin Chen
University of Electronic Science and Technology of China
- JHJiajia He
University of Electronic Science and Technology of China
- YLYi Li
University of Electronic Science and Technology of China
- YFYunlin Feng
University of Electronic Science and Technology of China
Topics & keywords
- Medicine
- Nephrology
- Acute kidney injury
- Intensive care medicine
- Internal medicine